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Rabu, 16 Februari 2011

Beberapa Orang Terlahir sebagai Pesimis

Kedengarannya menyedihkan, tetapi sepertinya ada di antara kita yang memang terlahir sebagai orang yang pesimistis.
Orang, yang secara genetis mudah memproduksi zat kimia otak yang mengontrol selera dan stres dalam jumlah sedikit, memiliki risiko lebih besar untuk terkena depresi berat, kata para peneliti.

Zat yang disebut sebagai molekul neuropeptida Y (NPY) tersebut mengatur respons otak terhadap rangsangan negatif dan respons terhadap rasa sakit.
Menurut peneliti dari University of Michigan, Amerika Serikat, temuan ini bisa menjadi diagnosis awal untuk mengatasi depresi dan penyakit kejiwaan lainnya.

"Kami berhasil mengidentifikasi sebuah penanda biologis—dalam hal ini variasi genetis—yang terkait dengan tingginya kasus depresi," kata Jon-Kar Zubieta, anggota tim peneliti, seperti dilansir Daily Mail.
Penelitian yang diterbitkan dalam jurnal Archives of General Psychiatry ini menggunakan tiga metode. Pertama, peneliti mengelompokkan subyek sukarelawan menjadi tiga kategori berdasarkan ekspresi NPY-nya: rendah, sedang, dan tinggi.

Lalu, menggunakan instrumen pencitraan resonansi magnetik (MRI), otak sukarelawan yang dipaparkan pada beberapa kata berbeda—ada yang bermakna netral (seperti benda), ada yang negatif (bunuh), dan ada yang positif (harapan) —dianalisis.

Hasilnya, grup sukarelawan dengan NPY rendah menunjukkan peningkatan aktivitas korteks prefrontal (bagian yang berkaitan dengan emosi), sementara grup dengan NPY tinggi menunjukkan respons lebih ringan.
Percobaan kedua adalah memberikan rasa sakit selama 20 menit dengan menggunakan cairan saline yang disuntikkan ke otot-otot rahang sukarelawan. Hasilnya sama: kelompok NPY rendah amat terpengaruh secara emosional sebelum dan sesudah rasa sakit.

BERBICARA PADA DIRI SENDIRI


Tanpa kita sadari, ternyata diri juga butuh untuk diajak bicara. Karena ternyata, dengan mengajak diri berbicara kita telah memberikan kesempatan untuk memperkaya diri.
Menurut para ahli, kebiasaan berbicara dengan diri sendiri atau self talk sudah ada sejak kita belajar bicara dan merupakan bagian dari proses belajar anak. Dan bicara dengan diri sendiri, tidak melulu dalam bentuk dialog dengan suara. Sebab semua yang terlintas dalam otak kita, sebenarnya cara kita berbicara dengan diri sendiri.
Maka jangan heran jika dalam satu menit, ada 150-300 kata. Itu artinya, 45-51 ribu kata per hari, total kata yang kita ucapkan setiap harinya pada diri kita sendiri. Menurut psikolog Toge Aprilianto dari Surabaya, berbicara pada diri sendiri bisa menjadi sangat dominan dalam diri setiap orang. Dan jika kita terbiasa berbicara pada diri sendiri akan memberikan banyak kelebihan, diantaranya:
1. Penyaluran emosi : Menggerutu karena lama menunggu adalah contoh dari berbicara dengan diri sendiri untuk menyalurkan emosi. Hanya saja, pastikan agar jangan sampai komunikasi dengan diri sendiri ini malah membuat kita semakin kesal.
2. Alat bantu mengambil keputusan : Semua faktor yang ada ketika kita dihadapkan pada dua kondisi untuk dipilih bisa dibicarakan pada diri sendiri dengan lebih fair.
3. Mengenal dan menerima diri sendiri : Berbicara dengan diri sendiri membuat kita lebih akrab dengan diri sendiri. Ini akan membantu kita tidak ikut terseret menjadi orang kebanyakan, karena kita lebih bisa mendengar kata hati kita ketika masuk dalam situasi atau lingkungan baru.
4. Berinteraksi dengan orang lain : Berbicara dengan diri sendiri akan menjadi media menimbang kebutuhan sendiri, mengira-ngira apakah orang lain bisa memenuhi kebutuhan kita, menimbang risikonya kalau ada untuk kemudian dijadikan referensi mengambil tindakan.
5. Memengaruhi orang lain dengan sehat: Sebelum menyakini orang lain, kita harus menyakinkan diri sendiri atau hal yang diinginkan dan direncanakan. Kalau kita tidak tahu apa yang kita mau, bagaimana bank akan percaya pada kita? Maka ajukanlah banyak pertanyaan kepada diri sendiri dulu, baru menyakinkan menyakinkan orang lain.
6. Mengembangkan diri : Berbicara dengan diri sendiri dapat menjadi media mengembangkan diri, jika kita menggunakan nada positif sama ketika kita menggunakannya untuk penyaluran emosi.

Sabtu, 29 Januari 2011

HITUNG JUMLAH RETIKULOSIT

Retikulosit adalah eritrosit muda yang sitoplasmanya mengandung sejumlah besar sisa-sisa ribosom dan RNA, dan berasal dari sisa inti dari bentuk penuh pendahulunya. Ribosom mempunyai kemampuan utnuk bereaksi dengan cat tertentu seperti briliant cresyl blue atau new methylene blue untuk membentuk endapan grnaula atau filament yang berwarna biru. Reaksi ini hanya terjadi pada pewarnaan terhadap sel yang masih hidup dan tidak difiksasi. Oleh karena itu disebut pewarnaan supravital. Retikulosit paling muda (imatur) adalah yang mengandung ribosom terbanyak. Sebaliknya retikulosit tertua hanya mempunyai beberapa titik rinosome. Banyak retikulosit dalam darah tepi menggambarkan aktivitas eritropoiesis yang hampir akurat. Hitung retikulosit dinyatakan sebagai prosentase jumlah retikulosit per 1000 eritrosit. Nilai normalnya 0,5 - 1,5 %.

a. Dasar

Darah dicampur dengan karutan brilliant cresyl blue atau larutan new methylene blue, lalu dibuat sediaan apus dan jumlah retikulositnya dihitung di bawah mikroskop. Jumlah retikulosit dihitung per 1000 eritrosit dan dinyatakan dalam %.

b. Peralatan dan Pereaksi

  • pewarnaan retikulosit dapat dilakukan dengan salah satu cat berikut:
    • larutan new methylene blue :
      • Natrium Klorida 0,8 gr
      • Kalium Oxalate 1,4 gr
      • New methylen blue 0,5 gr
      • aquadest 100 ml

    • larutan brilliant cresyl blue :
      • brilliant cresyl blue 1,0 gr
      • Na sitrat 20 ml
      • Natrium Clorida 0,85% 80 ml


  • saring kedua cat tersebut sebelum digunakan
  • kaca obyek
  • tabung reaksi kecil
  • pipet pasteur atau tabung mikrohematokrit
  • mikroskope

c. spesimen

darah kapiler , darah EDTA atau darah segar

d. Cara Kerja

  • ke dalam tabung reaksi kecil tetskan 2btetes larutan brilliant cresyl blue dalam natrium citrat atau new methylene blue.
  • tembahkan 4 tetes darah, campurkan baik-baik dan biarkan selama15 menit agar pewarnaan sempurna
  • inkubasi 37 derajat Celcius selama 15 menit, tabung tersebut kocok sekali lagi dan ambil setetes dengan pipit pasteur untuk dibuatn sediaan darah apus. Keringkan di udara dan periksalah dengan mikroskop.
  • periksalah dengan perbesaran obyektif 100 kali. Carilah daerah yang cukup tipis di mana eritrosit tidak membuat reuleaux. Eritrosit biru muda dan retikulasit akan tumpak sebagai sel yang mengandung granula / filament biru. Bila kurang jelas bisa di counterstain (dicat lagi) dengan cat wright
  • hitung dalam 1000 eritrosit dengan mempersempit lapangan pandang (letakkan kertas dengan lubang di dalam okuler)

e. Perhitungan







jumlah retikulosit =








jumlah retulosit
1000 eritrosit

x 100 %

g. Nilai Normal Dacie ; 0,5 - 1,5 %

HITUNG TROMBOSIT

Metode untuk menghitung trombosit telah banyak dibuat dan jumlahnya tergantung dari kenyataan bahwa sukar untuk menghitung sel-sel trombosit yang merupakan partikel kecil dan mudah aglutinasi maupun mudah pecah. Sukar untuk membedakan dengan kuman. Metode elektronik mempunyai ketelitian yang baik, tetapi metode visual yang langsung cukup dapat digunakan utnuk menghitung trombosit yang rendah sampai tinggi. Bila trombosit rendah, maka metode yang menggunakan plasma cukup bermakna. Metode elektronik tidak akan diuraikan.Yang akan dibahas dalam halaman ini adalah penghitungan trombosit dengan metode langsung (Rees-Ecker).

a. Prinsip

Darah diencerkan ke dalam larutan yang mengandung brilliant cresyl blue, sehingga trombosit tercat biru muda. Trombosit dihitung dengan bilik hitung. Hasil pemeriksaannya diperiksa ulang dengan sediaan apus.

b. spesimen

Darah EDTA atau darh kapiler

c. Peralatan dan Pereaksi

  • larutan pengencer trombosit (Rees-Ecker)
    • Natrium Sitrat 3,8 gr
    • brillian cresyl blue 0,1 gr
    • Formaldehid 40% 0,2 gr
    • Aquadest 100 ml
    • salinlah sebelum digunakan

  • pipet eritrosit
  • bilik hitung
  • kaca Obyek, cat wright dan larutan penyangga fosfat
  • mikroskop
  • cawan petri
  • kertas saring / tissue

d. Cara Kerja

hisaplah darah dengan pipet erotrosit sampai tanda 0,5 dan encerkan dengan larutan pengencer sampai tanda 101 (pengenceran 200x). Mulai saat ini trombosit harus selesai dihitung dalam waktu 30 menit, agar tidak terjadi disintegrasi sel-sel trombosit

kocoklah pipet tersebut 3-5 menit

bersihkan bilik hitung

siapkanlah cawan petri bagian dalam, dasar dan tutupnya ditempeli kapas yang ukurannya sama dan sebelumnya telah dibasahi air

setelah pipet tersebut dikocok, buanglah 4 tetes pertama dan tetesan ke lima isikan ke dalam bilik hitung. masukkan bilik hitung tersebut ke dalam cawan petri yang telah disiapkan tadi. Biarkan selama 15 menit , agar trombosit mengendap dan tidak terjadi penguapan.

letakkan bilik hitung di bawah mikroskop dengan perbesaran 100X obyektif dan kemudian perbesaran 40 x , trombosit tampak refraktif dan mengkilat berwarna biru muda / nila, lebih kecil dari eritrosit serta bentuk bulat, lonjong atau tersebar atau bergerombol.

perhitungan:






jumlah trombosit =








rata-rata jumlah trombosit tiap kotak X pengenceran
volume kotak trombosit(kotak kecil)


buatlah sediaan apus dengan pewarnaan Wright dan amati kesan jumlah trombosit sebagai periksa ulang terhadap metode di atas

PEMERIKSAAN HITUNG JUMLAH LEUKOSIT

        Hitung leukosit menyatakan jumlah sel-sel leukosit perliter darah (System International Units = SI unit) atau per satu mmk darah. Nilai normalnya 4000 - 11000 / mmk.Untuk penerapan hitung leukosit ada dua metode, manual dan elektronik. Pada umumnya metode elektronik belum digunakan secara umum, mungkin baru di laboratorium besar, sehingga cara manual masih memegang peranan penting. Metode elektronik tidak dibicarakan.

a. Dasar

Darah diencerkan dengan larutan asam lemah, yang menyebabkan sel-sel erotrosit hemolisis serta darah menjadi encer, sehingga sel-sel leukosit mudah dihitung.

b. Peralatan :

1. haemocytometer

  • bilik hitung
  • pipet leukosit
  • pipet eritrosit (untuk menghitung eritrosit)

Bilik Hitung adalah bilik hitung Neubauer Improve atau Burker karena mempunyai daerah perhitungan yang luas.

burker : luas seluruh bilik : 3x 3 mm2. di dalam bilik terdapat :

  • kotak besar : 1 x 1 mm2
  • kotak sedang : 1/5 x 1/5 mm2
  • kotak kecil : 1/20 x 1/20 mm2

Neubauer Improve : luas seluruh bilik 3 x 3 mm2. tinggi/dalam 0,1 mm. di dalam bilik terdapat :

  • kotak besar : 1 x 1 mm2
  • kotak sedang ada 2 macam :
    • di tengah : 1/5 x 1/5 mm2
    • di empat sudut : 1/4 x 1/4 mm2

  • kotak kecil : 1/20 x 1/20 mm2

pipet leukosit didalamnya terdapat bola berwarna putih, mempunyai garis 0,5 - 1 - 11

2. kaca penutup

3. mikroskop

c. Larutan pengencer yang dapat digunakan salah satunya larutan truk

  • asam asetat glacial 2 ml
  • gentian violet 1 ml
  • aquades 100 ml

d. Spesimen

Darah vena atau darah kapiler

e. Cara Kerja

  • Bilik hitung dicari dengan menggunakan mikroskop, cari kotak sedang di tempat ujung bilik hitung
  • hisap darah dengan pipet leukosit sampai angka 1 (pengenceran = 10x) atau sampai angka 5 (pengenceran = 20x)
  • hapus darah yang melekat pada ujung pipet
  • kenudian dengan pipet yang sama hisap larutan truk sampai angka 11
  • campur (kocok) secara horisontal
  • buang tetesan pertama
  • tuangkan dalam bilik hitung yang telah ditutup dengan kaca penutup dan diletakkan di mikroskop
  • lakukan perhitungan sel leukosit dengan perbesaran obyektif 10 atau 40 x.

f. Perhitungan






jumlah leukosit =







rata-rata jumlah leukosit tiap kotak X pengenceran
volume tiap kotak

g. Nilai Normal menurut Dacie

  • dewasa pria : 4 - 11 ribu/mmk
  • dewasa wanita : 4 - 11 ribu/mmk
  • bayi : 10 -25 ribu/mmk
  • 1 tahun: 6 - 18 ribu/mmk
  • 12 tahun : 4,5 - 13 ribu/mmk


              Sel darah putih, leukosit (en:white blood cell, WBC, leukocyte) adalah sel yang membentuk komponen darah. Sel darah putih ini berfungsi untuk membantu tubuh melawan berbagai penyakit infeksi sebagai bagian dari sistem kekebalan tubuh. Sel darah putih tidak berwarna, memiliki inti, dapat bergerak secara amoebeid, dan dapat menembus dinding kapiler / diapedesis. Dalam keadaan normalnya terkandung 4x109 hingga 11x109 sel darah putih di dalam seliter darah manusia dewasa yang sehat - sekitar 7000-25000 sel per tetes.Dalam setiap milimeter kubil darah terdapat 6000 sampai 10000(rata-rata 8000) sel darah putih .Dalam kasus leukemia, jumlahnya dapat meningkat hingga 50000 sel per tetes.
Di dalam tubuh, leukosit tidak berasosiasi secara ketat dengan organ atau jaringan tertentu, mereka bekerja secara independen seperti organisme sel tunggal. Leukosit mampu bergerak secara bebas dan berinteraksi dan menangkap serpihan seluler, partikel asing, atau mikroorganisme penyusup. Selain itu, leukosit tidak bisa membelah diri atau bereproduksi dengan cara mereka sendiri, melainkan mereka adalah produk dari sel punca hematopoietic pluripotent yang ada pada sumsum tulang.
Leukosit turunan meliputi: sel NK, sel biang, eosinofil, basofil, dan fagosit termasuk makrofaga, neutrofil, dan sel dendritik.

Jenis

Ada beberapa jenis sel darah putih yang disebut granulosit atau sel polimorfonuklear yaitu:[1]
dan dua jenis yang lain tanpa granula dalam sitoplasma:
Tipe Gambar Diagram % dalam tubuh manusia Keterangan
Neutrofil PBNeutrophil.jpg Neutrophil.png 65% Neutrofil berhubungan dengan pertahanan tubuh terhadap infeksi bakteri serta proses peradangan kecil lainnya, serta biasanya juga yang memberikan tanggapan pertama terhadap infeksi bakteri; aktivitas dan matinya neutrofil dalam jumlah yang banyak menyebabkan adanya nanah.
Eosinofil Eosinophil.jpg Eosinophil2.png 4% Eosinofil terutama berhubungan dengan infeksi parasit, dengan demikian meningkatnya eosinofil menandakan banyaknya parasit.
Basofil PBBasophil.jpg Basophil.png <1% Basofil terutama bertanggung jawab untuk memberi reaksi alergi dan antigen dengan jalan mengeluarkan histaminperadangan. kimia yang menyebabkan
Limfosit Lymphocyte2.jpg Lymphocyte.png 25% Limfosit lebih umum dalam sistem limfa. Darah mempunyai tiga jenis limfosit:
  • Sel B: Sel B membuat antibodi yang mengikat patogen lalu menghancurkannya. (Sel B tidak hanya membuat antibodi yang dapat mengikat patogen, tapi setelah adanya serangan, beberapa sel B akan mempertahankan kemampuannya dalam menghasilkan antibodi sebagai layanan sistem 'memori'.)
  • Sel T: CD4+ (pembantu) Sel T mengkoordinir tanggapan ketahanan (yang bertahan dalam infeksi HIV) sarta penting untuk menahan bakteri intraseluler. CD8+ (sitotoksik) dapat membunuh sel yang terinfeksi virus.
  • Sel natural killer: Sel pembunuh alami (natural killer, NK) dapat membunuh sel tubuh yang tidak menunjukkan sinyal bahwa dia tidak boleh dibunuh karena telah terinfeksi virus atau telah menjadi kanker.
Monosit
Monocyte.png 6% Monosit membagi fungsi "pembersih vakum" (fagositosis) dari neutrofil, tetapi lebih jauh dia hidup dengan tugas tambahan: memberikan potongan patogen kepada sel T sehingga patogen tersebut dapat dihafal dan dibunuh, atau dapat membuat tanggapan antibodi untuk menjaga.
Makrofag Macrophage.jpg Macrophage.png (lihat di atas) Monosit dikenal juga sebagai makrofag setelah dia meninggalkan aliran darah serta masuk ke dalam jaringan.



Fungsi sel Darah putih

Granulosit dan Monosit mempunyai peranan penting dalam perlindungan badan terhadap mikroorganisme. dengan kemampuannya sebagai fagosit (fago- memakan), mereka memakan bakteria hidup yang masuk ke sistem peredaran darah. melalui mikroskop adakalanya dapat dijumpai sebanyak 10-20 mikroorganismegranulosit. pada waktu menjalankan fungsi ini mereka disebut fagosit. dengan kekuatan gerakan amuboidnya ia dapat bergerak bebas didalam dan dapat keluar pembuluh darah dan berjalan mengitari seluruh bagian tubuh. dengan cara ini ia dapat: tertelan oleh sebutir
Mengepung daerah yang terkena infeksi atau cidera, menangkap organisme hidup dan menghancurkannya,menyingkirkan bahan lain seperti kotoran-kotoran, serpihan-serpihan dan lainnya, dengan cara yang sama, dan sebagai granulosit memiliki enzim yang dapat memecah protein, yang memungkinkan merusak jaringan hidup, menghancurkan dan membuangnya. dengan cara ini jaringan yang sakit atau terluka dapat dibuang dan penyembuhannya dimungkinkan
Sebagai hasil kerja fagositik dari sel darah putih, peradangan dapat dihentikan sama sekali. Bila kegiatannya tidak berhasil dengan sempurna, maka dapat terbentuk nanah. Nanah beisi "jenazah" dari kawan dan lawan - fagosit yang terbunuh dalam kinerjanya disebut sel nanah. demikian juga terdapat banyak kuman yang mati dalam nanah itu dan ditambah lagi dengan sejumlah besar jaringan yang sudah mencair. dan sel nanah tersebut akan disingkirkan oleh granulosit yang sehat yang bekerja sebagai fagosit.

Sel jaringan lainnya

  • Histiosit, ada dalam sistem limfa bersama jarigan lainnya, tetapi tidak umum di dalam darah:
    • Makrofaga
    • Sel dendritik
  • Mastosit                                                                                                                                              

Rabu, 26 Januari 2011

Eenie Meenie

Featuring: Sean Kingston

Eenie, meenie, miney, mo
Catch a bad chick by her toe
If she holla
If, if, if she holla, let her go

She's indecisive, she can't decide
She keeps on looking from left to right
Girl, come a bit closer, look in my eyes
Searching is so wrong, I'm Mr. Right

You seem like the type to love 'em and leave 'em
And disappear right after this song
So give me the night to show you, hold you
Don't leave me out here dancin' alone

You can't make up your mind, mind, mind, mind, mind
Please don't waste my time, time, time, time, time
I'm not tryin' to rewind, wind, wind, wind, wind
I wish our hearts could come together as one

'Cause shorty is a eenie, meenie, miney, mo, lova
Shorty is a eenie, meenie, miney, mo, lova
Shorty is a eenie, meenie, miney, mo, lova
Shorty is a eenie, meenie, miney, mo, lova

Let me show you what you're missing, paradise
With me you're winning, girl, you don't have to roll the dice
Tell me what you're really here for
Them other guys? I can see right through ya

You seem like the type to love them and leave them
[ From : http://www.elyrics.net/read/j/justin-bieber-lyrics/eenie-meenie-lyrics.html ]
And disappear right after the song
So give me the night to show you, hold you
Don't leave me out here dancing alone

Can't make up your mind
Please don't waste my time
Not trying to rewind
I wish our hearts could come together as one

'Cause shorty is a eenie, meenie, miney, mo, lova
Shorty is a eenie, meenie, miney, mo, lova
Shorty is a eenie, meenie, miney, mo, lova
Shorty is a eenie, meenie, miney, mo, lova

Eenie, meenie, miney, mo
Catch a bad chick by her toe
If she holla
If, if, if she holla, let her go

Eenie, meenie, miney, mo
Catch a bad chick by her toe
If she holla, lolla, lolla
Let her go

Shorty is a eenie, meenie, miney, mo, lova
Shorty is a eenie, meenie, miney, mo, lova
Shorty is a eenie, meenie, miney, mo, lova
Shorty is a eenie, meenie, miney, mo, lova

Can't make up your mind
Please don't waste my time
I'm not trying to rewind
I wish our hearts could come together as one

Shorty is a eenie, meenie, miney, mo, lova
Shorty is a eenie, meenie, miney, mo, lova
Shorty is a eenie, meenie, miney, mo, lova
Shorty is a eenie, meenie, miney, mo, lova













Favorite Girl

I always knew you were the best
The coolest girl I know
So prettier than all the rest
The star of my show

So many times I wished
You'd be the one for me
But never knew it'd get like this
Girl, what you do to me

You're who I'm thinkin' of
Girl, you ain't my runner up
And no matter what
You're always number one

My prize possession, one and only
Adore you girl, I want you
The one I can't live without
That's you, that's you

You're my special little lady
The one that makes me crazy
Of all the girls I've ever known
It's you, it's you

My favorite, my favorite
My favorite, my favorite girl
My favorite girl

You're used to goin' out your way
To impress these Mr. Wrongs
But you can be yourself with me
I'll take you as you are

I know they said believe in love
It's a dream that can't be real
So girl let's write a fairytale
And show 'em how we feel

You're who I'm thinkin' of
Girl you ain't my runner up
And no matter what
You're always number one

My prize possession, one and only
Adore you girl, I want you
The one I can't live without
That's you, that's you

You're my special little lady
[ From: http://www.elyrics.net/read/j/justin-bieber-lyrics/favorite-girl-lyrics.html ]
The one that makes me crazy
Of all the girls I've ever known
It's you, it's you

My favorite, my favorite
My favorite, my favorite girl
My favorite girl
Baby it's you

My favorite, my favorite
My favorite, my favorite girl
My favorite girl

You take my breath away
With everything you say
I just wanna be with you
My baby, my baby, oh

My miss don't play no games
Treat you no other way
Than you deserve
'Cause you're the girl of my dreams

My prize possession, one and only
Adore you girl, I want you
The one I can't live without
That's you, that's you

You're my special little lady
The one that makes me crazy
Of all the girls I've ever known
It's you, it's you

My prize possession, one and only
Adore you girl, I want you
The one I can't live without
That's you, that's you

You're my special little lady
The one that makes me crazy
Of all the girls I've ever known
It's you, it's you

You're my favorite girl
(My favorite, my favorite)
Favorite girl, favorite girl, favorite girl
(My favorite, my favorite girl, my favorite girl)

Favorite girl, favorite girl, favorite girl
(My favorite, my favorite, my favorite)
(My favorite girl, my favorite girl)
Favorite girl


First Dance

Usher: It's your chance take her hand to the floor
(fellas just the moment you've been waiting for)
Girl if you see something you like then let 'em know
(ladies i know your ready)
Cuz you only got one chance
(yeah yeah)
For your first dance
(you never forget bout your first dance)
So take advantage of the slow jam
(tell 'em J.B.)yeah, man

Justin: when I close my eyes,
I see me and you at the prom
We've both been waiting so long
For this day to come
Now that its here
Let's make it special

(I can't deny)
There's so many thoughts in my mind
The D.J.'s playing my favorite song(favorite song)
Ain't no chaperones(chaperones)
This could be the night of your dreams

CHORUS:
Only if you give, give the first dance to me
Girl I promise I'll be gentle
I know we gotta do it slowly
If you give, give the first dance to me
I'm gonna' cherish every moment
'Cuz it only happens once, once in a lifetime

I couldn't ask for more
We're rocking back and forth
Under the disco ball
We're the only ones on the floor

(I can't deny)
There's so many thought in my mind
The D.J.'s playing my favorite song (favorite song)
Now we're all alone (all alone)
Here's the opportunity
[ From : http://www.elyrics.net/read/j/justin-bieber-lyrics/first-dance-lyrics.html ]

Only if you give, give the first dance to me
Girl I promise I'll be gentle
I know we gotta do it slowly
If you give, give the first dance to me
I'm gonna' cherish every moment
Cuz it only happens once once in a lifetime

Everybody says that we look cute together
Let's make this a night the two of us remember
No teachers around to see us dancing close
I'm telling you our parents will never know
Before the lights go up
And the music turns off
Now's the perfect time for me to taste your lip gloss
your glass slippers in my hand right here
We'll make it before the clock strikes nine

If you just give give the first dance to me
Girl I promise I'll be gentle
(i know)But we gotta do it slowly
If you give, give the first dance to me
(give the first dance baby)
I'm gonna' cherish every moment
Cuz it only happens once, once in a lifetime

Usher: it's your chance take her hand to the floor (to the floor)
girl, if you see something you like then let 'em know
cuz you only got one chance, for your first dance
so take advantage of this slow down
yeah man.

If you give, give the first dance to me
I'm gonna' cherish every moment
Cuz it only happens once, once in a lifetime

I'll Be

The strands in your eyes
That color them wonderful
Stop me was stealing my breath
The emeralds from mountains
The thrust toward the sky
Never revealing their depth
Tell me
That we belong together
Dress it up with the trappings of love
I’ll be captivated
I’ll hang from your lips
Instead of the gallows of heartbreak
That hang from above

Chorus:
What day is it
And in what month
This clocks never seems so alive
And I can't keep up
And I can't back down
[ From: http://www.elyrics.net/read/j/justin-bieber-lyrics/i_ll-be-lyrics.html ]
I've been losing so much time
Cause it's you and me
And all of the people
And nothing to do
Nothing to lose
And it's you and me
I've dropped out
I've burned up
I've fought my way back from the dead
I've turned in
I've turned on
I've saw all of the things I've said
And I'll be your crying shoulder
I'll be love suicide
And I'll be better when I'm older
I'll be the greatest fan of your life
Greatest fan of your life


Kiss And Tell lyrics


Yeah
J-J-J JB Yeah
Woaah woahh
Nooo, noo

[Verse 1:]

Now I can see you girl
You ain't gotta say nothing
Your lips are callin me
Like they wanna do something

I feel the chemistry
Girl you're into me
A little kiss is a definite possibility

Seen you a couple times
Had a couple conversations
Since you have been on my mind
Made a couple observations

Like you a fly chick
You could be my chick
Play by rules and you can get what I get

[Bridge:]

Just keep it quiet, keep it on the hush (Yeah, yeah)
And what we do keep it just between us (Yeah, yeah)
I don't wanna see you tweet about JB,
'Coz the only people that should know was you and me so

[Chorus:]

Baby, I know that you're cool with rockin with me
But I can't have you tellin everybody
You got me all kissin with your lips like this so
Tell me, tell me are you gonna kiss
(Kiss) kiss and tell?
Tell me are you gonna kiss
(Kiss) kiss and tell?
Tell me are you gonna kiss me then tell everybody
That you got me twisted with your lips girl,
Are you gonna kiss and tell?

[Verse 2:]

It's confidential, no one has to do with it
But you and me girl, tell'em we'll ruin it
Don't need that tmz, all in our privacy
Use them lips for kissin girl if you wanna ride with me

And if you wanna tell somebody
Then we can call the whole thing off (No Problem)
You can go your way and I'll go mine,
But I rather spend a little time with you (yeah)

[Bridge:]

Just keep it quiet, keep it on the hush (Yeah, yeah)
[From: http://www.elyrics.net/read/j/justin-bieber-lyrics/kiss-and-tell-lyrics.html]
And what we do keep it just between us (Yeah, yeah)
I don't wanna see you tweet about JB,
'Coz only people that you know was you and me so

[Chorus:]

Baby, I know that you're cool with rockin with me
But I can't have you tellin everybody
You got me all kissin with your lips like this so
Tell me, tell me are you gonna kiss
(Kiss) kiss and tell?
Tell me are you gonna kiss
(Kiss) kiss and tell?
Tell me are you gonna kiss me then tell everybody
That you got me twisted with your lips girl,
Are you gonna kiss and tell?

[Verse 3:]

Tell said, are you gonna kiss and tell?
Tell said, are you gonna kiss and tell?
Tell said, are you gonna kiss and tell?
Kiss and tell (Oohh)

Don't tell your homies
Don't tell your mama
Don't tell your girlfriend
That'll start some drama

Stay off that facebook, I'll treat you real good
You keep this private and you can get what i get (ohh)

[Chorus:]

Baby, I know that you're cool with rockin with me
But I can't have you tellin everybody
You got me all kissin with your lips like this so
Tell me, tell me are you gonna kiss
(Kiss) kiss and tell?
Tell me are you gonna kiss
(Kiss) kiss and tell?
Tell me are you gonna kiss me then tell everybody
That you got me twisted with your lips girl,
Are you gonna kiss and tell?

Woah (kiss and tell)
Woah woahh

I'm not about that, if you're gonna kiss and tell
Noo noo no,
if you're gonna kiss and tell,
if you're gonna kiss and tell,
That's not me.


One Less Lonely Girl lyrics
Alright, let's go

There's gonna be one less lonely girl
(One less lonely girl)
One less lonely girl
(One less lonely girl)

There's gonna be one less lonely girl
(One less lonely girl)
One less lonely girl

How many I told yous and start overs and shoulders
Have you cried on before?
How many promises, be honest girl
How many tears you let hit the floor?

How many bags you packed, just to take him back
Tell me that how many either ors
But no more if you let me inside of your inside your world
There'll be one less lonely girl

Saw so many pretty faces before I saw you, you
Now all I see is you
I'm coming for you
(I'm coming for you)

Don't need these other pretty faces like I need you
And when you're mine in the world
There's gonna be one less lonely girl

I'm coming for you, one less lonely girl
I'm coming for you, one less lonely girl
I'm coming for you, one less lonely girl
There's gonna be one less lonely girl

I'm coming for you, I'm gonna put you first
I'm coming for you, I'll show you what you're worth
That's what I'm gonna do, if you let me inside of your world
There's gonna be one less lonely girl

Christmas wasn't merry, 14th of February
Not one of 'em spent with you
How many dinner dates, set dinner plates
And he didn't even touch his food?

How many torn photographs I saw you taping back
Tell me that you couldn't see an open door
But no more, if you let me inside your world
There'll be one less lonely girl

Saw so many pretty faces before I saw you, you
Now all I see is you
I'm coming for you, I'm coming for you

Don't need these other pretty faces like I need you
{ From: http://www.elyrics.net/read/j/justin-bieber-lyrics/one-less-lonely-girl-lyrics.html }
And when you're mine in this world
There's gonna be one less lonely girl

I'm coming for you, one less lonely girl
I'm coming for you, one less lonely girl
I'm coming for you, one less lonely girl
There's gonna be one less lonely girl

I'm coming for you, I'm gonna put you first
I'm coming for you, I'll show you what you're worth
That's what I'm gonna do, if you let me inside your world
There's gonna be one less lonely girl

I can fix up your broken heart
I can give you a brand new start
I can make you believe, yeah
I just wanna set one girl free to fall, free to fall
She's free to fall, fall in love with me

Her heart's locked, and know what, I got the key
I'll take her and leave the world with one less lonely

There's gonna be one less lonely girl
One less lonely girl
One less lonely girl
One less lonely girl

There's gonna be one less lonely girl
One less lonely girl
One less lonely girl

I'm coming for you, one less lonely girl
I'm coming for you, one less lonely girl
I'm coming for you, one less lonely girl
There's gonna be one less lonely girl

I'm coming for you, I'm gonna put you first
I'm coming for you, I'll show you what you're worth
That's what I'm gonna do, if you let me inside your world
There's gonna be one less lonely girl

I'm coming for you, one less lonely girl
I'm coming for you, one less lonely girl
I'm coming for you, one less lonely girl
There's gonna be one less lonely girl

I'm coming for you, I'm gonna put you first
I'm coming for you, I'll show you what you're worth
That's what I'm gonna do, if you let me inside your world
There's gonna be one less lonely girl

Only you shawty


Never Say Never lyrics

See I never thought that I could walk through fire
I never thought that I could take the burn
I never had the strength to take it higher
Until I reached the point of no return

And there's just no turning back
When your heart's under attack
Gonna give everything I have
It's my destiny

I will never say never
(I will fight)
I will fight till forever
(Make it right)

Whenever you knock me down
I will not stay on the ground
Pick it up, pick it up
Pick it up, pick it up
Up, up, up, up, up and never say never

Ne-never say never
Ne-never say never
Ne-never say never

I never thought I could feel this power
I never thought that I could feel this free
I'm strong enough to climb the highest tower
And I'm fast enough to run across the sea

And there's just no turning back
When your hearts under attack
Gonna give everything I have
'Cause this is my destiny

I will never say never
(I will fight)
I will fight till forever
(Make it right)

Whenever you knock me down
I will not stay on the ground
Pick it up, pick it up
Pick it up, pick it up
Up, up, up, up, up and never say never

Ne-never say never
Ne-never say never
Ne-never say never

Here we go, guess who?
J Smith and JB
I gotcha lil bro, I can handle him
Hold up, aight? I can handle him

Now he's bigger than me, taller than me
And he's older than me and stronger than me
And his arms a little bit longer than me
But he ain't on a JB song with me

I be trying a chill
They be trying to side with the thrill
No pun intended
Was raised by the power of Will

Like Luke with the Force
When push comes to shove
Like Kobe with the fourth
Ice water with blood

I gotta be the best, and yes
We're the fliest like David and Goliath
I conquered the giant
So now I got the world in my hand
I was born from two stars
So the moon's where I land

I will never say never
(I will fight)
I will fight till forever
(Make it right)

Whenever you knock me down
I will not stay on the ground
Pick it up pick it up
Pick it up pick it up
Up, up, up, up, up and never say never

Ne-never say never
Ne-never say never
Ne-never say never

I will never say never
(I will fight)
I will fight till forever
(Make it right)

Whenever you knock me down
I will not stay on the ground
Pick it up pick it up
Pick it up pick it up
Up, up, up, up, up aad never say never

Ne-never say never
Ne-never say never
Ne-never say never

Never say never

Never Let You Go lyrics

Oh no, oh no, oh

They say that hate has been sent
So let loose the talk of love
Before they outlaw the kiss
Baby, give me one last hug

There's a dream that I've been chasing
Want so badly for it to be reality
And when you hold my hand then I understand
That it's meant to be 'cause, baby, when you're with me

It's like an angel came by, oh and took me to heaven
Like you took me to heaven, girl
'Cause when I stare in your eyes it couldn't be better
I don't want you to go, oh no, so

Let the music blast, we gon' do our dance
Bring the doubters on, they don't matter at all
'Cause this life's too long and this love's too strong
So baby, know for sure that I'll never let you go

I got my favorite girl
Not feeling no pain, no fear
Don't have a care in the world
Why would I when you are here?

There's a moment I've been chasing
And I finally caught it out on this floor
Baby, there's no hesitation, no reservation
By taking a chance and more, oh no, because

It's like an angel came by and took me to heaven
[ From: http://www.elyrics.net/read/j/justin-bieber-lyrics/never-let-you-go-lyrics.html ]
Like you took me to heaven, girl
'Cause when I stare in your eyes, it couldn't be better
I don't want you to go, oh no, so

Let the music blast, we gon' do our dance
Bring the doubters on, they don't matter at all
'Cause this life's too long and this love's too strong
So baby, know for sure that I'll never let you go

It's like an angel came by and took me to heaven
Like you took me to heaven, girl
'Cause when I stare in your eyes, it couldn't be better
I don't want you to go, oh no, so

Take my hand, let's just dance
Watch my feet, follow me
Don't be scared, girl, I'm here
If you didn't know, this is love

Let the music blast, we gon' do our dance
Bring the doubters on, they don't matter at all, oh baby
'Cause this life's too long and this love's too strong
So baby, know for sure that I'll never let you go

So don't fear, don't you worry 'bout a thing
I am here, right here, I'll never let you go
Don't shed a tear whenever you need me
I'll be here, I'll never let you go

Oh no, oh no, oh
I'll never let you go


Oh no, oh no, oh
I'll never let you go



 Heartache lyrics

W... Wait
But yesterday we were...I don't understand?

We started out it was perfect
Nothing but fun
and my heart was convinced
to say that you're the one

And I thought it would last the rest of our lives
Boy was I in for a big surprise,
with no doubt looking round
thinking that I'm so cool

Same place, same time
every day of my life
could we meet after school?
Finally if I didn't make her cry
she wouldn't be with another guy

Nothing can cure my headache
cause I'm experiencing
what they call heartbreak
It's going to hurt worse
as long as I stay here
I know but man just let me lay here...

Cause this is something that I can't shake
I must be experiencing what they call heartbreak
They say it's only just as worse as you make it...
I know but man just let me lay here

Now I'm all tore up taking up
when I was at your door
The first time when you said
forever I'll be yours
Started walking your hand in my hand
feelings got stronger
We made a promise

And whenever I leave it feels like you're still with me
[ From: http://www.elyrics.net/read/j/justin-bieber-lyrics/heartache-lyrics.html ]
but it all came crashing down
Sitting in my room
I gotta get out of here
what am I to do when I look up
and you're not there

Nothing can cure my headache
cause I'm experiencing
what they call heartbreak
It's going to hurt worse
as long as I stay here
I know but man just let me lay here...

Cause this is something that I can't shake
I must be experiencing what they call heartbreak
They say it's only just as worse as you make it...
I know but man just let me lay here

Say I'm to young for love
I got so much live to live ahead
But if only this love?
I could get over
I know I have to deal with the pain

Nothing can cure my headache
cause I'm experiencing
what they call heartbreak
It's going to hurt worse
as long as I stay here
I know but man just let me lay here...

Cause this is something that I can't shake
I must be experiencing what they call heartbreak
They say it's only just as worse as you make it...
I know but man just let me lay here


One Time lyrics

Me plus you, I'ma tell you one time
Me plus you, I'ma tell you one time
Me plus you, I'ma tell you one time
One time, one time

When I met you girl my heart went knock knock
Now them butterflies in my stomach won't stop stop
And even though it's a struggle love is all we got
And we gon' keep keep climbing to the mountain top

Your world is my world
And my fight is your fight
My breath is your breath
And your heart

And girl you're my one love, my one heart
My one life for sure
Let me tell you one time
(Girl, I love, girl I love you)
I'ma tell you one time
(Girl, I love, girl I love you)

And I'ma be your one guy
You'll be my #1 girl
Always making time for you
I'ma tell you one time
(Girl, I love, girl I love you)
I'ma tell you one time
(Girl, I love, girl I love you)

You look so deep, you know that it humbles me
You're by my side, them troubles them not trouble me
Many have called but the chosen is you
Whatever you want shawty I'll give it to you

Your world is my world
And my fight is your fight
My breath is your breath
(From: http://www.elyrics.net/read/j/justin-bieber-lyrics/one-time-lyrics.html)
And your heart

And girl you're my one love, my one heart
My one life for sure
Let me tell you one time
(Girl, I love, girl I love you)
I'ma tell you one time
(Girl, I love, girl I love you)

And I'ma be your one guy
You'll be my #1 girl
Always making time for you
I'ma tell you one time
(Girl, I love, girl I love you)
I'ma tell you one time
(Girl, I love, girl I love you)

Shawty right there
She's got everything I need
And I'ma tell her one time
Give you everything you need down to my last dime

She makes me happy
I know where I'll be
Right by your side
'Cause she is the one

And girl you're my one love, my one heart
My one life for sure
Let me tell you one time
(Girl, I love, girl I love you)
I'ma tell you one time
(Girl, I love, girl I love you)

And I'ma be your one guy
You'll be my #1 girl
Always making time for you
I'ma tell you one time
(Girl, I love, girl I love you)
I'ma tell you one time
(Girl, I love, girl I love you)

Me plus you, I'ma tell you one time
Me plus you, I'ma tell you one time
Me plus you, I'ma tell you one time
One time, one time


Overboard (Ft. Jessica Jarrell) lyrics

It feels like we've been out at sea
So back and forth that's how it seems
Whoa and when I want to talk
you say to me
That if its meant to be, it will be
So crazy is this thing we call love
And now that we've got it we just can't give up
I'm reaching out for you
Got me out here in the water and I'm...

I'm overboard and I need your love
Pull me up
I can't swim on my own
It's too much
Feels like I'm drowning without your love
So throw yourself out to me
My life saver
Life saver
Oh life saver
My life saver
Life saver
Oh life saver oh wow

I never understood you when you'd say
You wanted me to meet you half way.
I felt like I was doing my part
You kept thinking you were coming up short
It's funny how things change
Cause now I see


So crazy is this thing we call love
And now that we got it
we just can't give up
I'm reaching out for ya
Got me out here in the water and I"m
[ From: http://www.elyrics.net/read/j/justin-bieber-lyrics/overboard-(Ft.-jessica-jarrell)-lyrics.html ]

I'm overboard
And I need your love
Pull me up (Pull me up)
I can't swim on my own
It's too much (It's too much)
Feels like I'm drowning without your love
So throw yourself out to me
My life saver

It's supposed to be some give and take I know.
But your only taking and not giving any more
So what do I do? (So what do I do?)
Cause I still love you. (Still love you Baby)
And you're the only one who can save me


I'm overboard
And I need your love
Pull me up (Pull me up)
I can't swim on my own
It's too much (It's too much)
Feels like I'm drowning (I'm drowning baby I'm
drowning)without your love
So throw yourself out to me (Can't swim)
My life saver
Life saver
Oh life saver
My life saver
(Its crazy, crazy crazy, yeah) Life saver
Oh life saver
Oh life saver
Oh life saver
Oh life saver
Yeah
Pick Me lyrics

Woah oh yeah
(Woah oh yeah)
Eh Eh
(we're chillin with the RCC - The Real Crystal Crew)
Woah oh oh yeah
You're the finest girl I've ever seen
And I wonder do you know this
That every guy you meet winds up catchin feelins for ya
You can have any of 'em
You can take your pick
But you need to check with me
Girl I promise I'm legit, yeah
Ya we'll be going to the movies
In the theater holding hands
I'll walk you home from school
I'll walk you to your classes
Playing my xbox 360 yes you'll you be my best friend
But most of all baby doll you'll be my love love love

You should be pick me
(So tell me can you dig it)
I'm everything you need girl
(So tell me can you dig it)
I'll always be your number one number one fan (dig that)
And I should be your one and only man
You should pick me
(So tell me can you dig it0
Think of how good that it could be girl
(So tell me can you dig it)
I'll always be your number one number one fan(dig that)
And I should be your one and only man
You should pick me

Yeah, you should pick me girl

You're my favorite part of the day
And every morning I look forward to me seeing your face
I just need to see it some more
Baby I'm the kind of guy who can appreciate a girl as
amazing as you
So you gotta be my baby girl
Cause' we'll already be chillin' at the beach
I'll take you on a cruise, watch sun set while we eat
[ From: http://www.elyrics.net/read/j/justin-bieber-lyrics/pick-me-lyrics.html ]
You can have anything you want cuz I'll be your best friend
But most of all baby doll you'll be my love love love

You should be pick me
(So tell me can you dig it)
I'm everything you need girl
(So tell me can you dig it)
I'll always be your number one number one fan (dig that)
And I should be your one and only man
You should pick me
(So tell me can you dig it)
Think of how good that it could be girl
(So tell me can you dig it)
I'll always be your number one number one fan (dig that)
And I should be your one and only man
You should pick me

You should pick the guy that makes you happy
Pick the flyest of 'em
Pick the one that's got swagger
Pick the one that makes you laugh
The one that always gots your back and
Who would rather die
Than make you sad

That's why you should pick me
(So tell me can you dig it)
I'm everything you need girl
(So tell me can you dig it)
I'll always be your number one number one fan (dig that)
And I should be your one and only man

You should pick me
(So tell me can you dig it)
Think of how that it could be girl
(So tell me can you dig it)
I'll always be your number one number one fan (dig that)
And i should be your one and only man
You should pick me

You should pick me
(the real crystal Crew)

Woah oh yeah
(Woah oh oh yeah)
Eh Eh
Woah oh oh yeah


Rich Girl (Feat. Soulja Boy) lyrics

She's a rich girl
Buying all the clothes
Wrist full of gold
You already know
She's a rich girl
Yeah, she's got cash
Pocket so thick
She ain't even gotta ask
Shes a rich girl
Rich girl
Shes a rich girl
Rich girl
Aye oh Aye oh Aye oh

When I met you girl
I tried to pay for dinner
Pulled out your card
I thought I had a winner
She said
Boy I got it
Then I said no
But I like a girl who's in control

She's my rich girl
Rich girl


She rides a barbie phantom
She lives in a barbie mansion
She's a rich girl
She got a lot of money
She credit card shawty
She credit card shopping
man Look good when she shoppin
Man she look good when she talking and she walkin
She walk like a model
She shop like a balla
She shop like a NFL, NBA, high school scholar



She's a rich girl
Buying all the clothes
Wrist full of gold
You already know
Shes a rich girl
Yeah, she's got cash
Pocket so thick
She ain't even gotta ask
Shes a rich girl
Rich girl
Shes a rich girl
Rich girl
Aye oh Aye oh Aye oh


21st birthday she got a louis mercedes
Drive top
Oh my god
Baby, I think I love you
Girl, I know you rich
and you know I rich so
Together we build things
Ill lend you it is empty
You can get it cuz I got plenty
Everyday, all night
[ From : http://www.elyrics.net/read/j/justin-bieber-lyrics/rich-girl-(Feat.-soulja-boy)-lyrics.html ]
you with me
And we ballin' yeah



She's a rich girl
Buying all the clothes
Wrist full of gold
You already know
She's a rich girl
Yeah, she's got cash
Pocket so thick
She ain't even gotta ask
She's a rich girl
Rich girl
She's a rich girl
Rich girl
Aye oh Aye oh Aye oh


Can't make you my queen
When I first met her
I didn't even have anything
She had more money than me
She wasn't a rich girl
grew up in a messed up world
And when i met her
She didn't think less of me
She get the bigger picture
She know we both --
We can't take it with us
We belong together
Yeah she's so special
Shes my rich girl
but if she was broke
I would still..
and my net froze
I told her I was hot
She told me that she cold
We are a tornado so we spin across the globe
I make money every day
& everybody surely knows
I'm a rich boy
a young pretty guy
Shes pretty fly
Shes pretty high
We're high together
we Make change whether x2
Hopes and I love her


She's a rich girl
Buying all the clothes
Wrist full of gold
You already know
Shes a rich girl
Yeah, she's got cash
Pocket so thick
She ain't even gotta ask
Shes a rich girl
Rich girl
Shes a rich girl
Rich girl

Soulja Boy I tell him
Aye yo aye yo aye yo
RICH GIRL!



Runaway Love lyrics

You see my baby up and hit the road
Where she's going that's when nobody knows
I need to find her 'fore another man does
I wouldn't want him to steal my love

I'm just trying to be cool, cool, cool, trying to be cool
What you expect me to do? Oh, oh, oh, yeah
I'm just trying to find, find, find
Sweet love of mine

I'm running out of time, where is my runaway love?
Searching low and high, know that I'm not giving up
I'd give it all up for us, it'll never be enough
I won't stop until I find my runaway love

See my baby really needs some help
'Cause she can never stay at home by herself
She says she needs a little company
Even if she's not always with me, yeah, oh

I'm just trying to be cool, cool, cool
What you expect me to do? Oh yeah
( From: http://www.elyrics.net/read/j/justin-bieber-lyrics/runaway-love-lyrics.html )
I'm just trying to find, find, find
Sweet love of mine

Running out of time, where is my runaway love?
Searching low and high, know that I'm not giving up
I'd give it all up for us, it'll never be enough
I won't stop until I find my runaway love

Why can't I find the love of mine
When you're standing right in front of my face?
Oh why? I must be blind
How did I let you get away? Yeah, yeah

I'm running out of time, where is my runaway love?
Searching low and high, know that I'm not giving up
I'd give it all up for us, it'll never be enough
I won't stop until I find my runaway love

Running out of time, where is my runaway love?
Searching low and high, know that I'm not giving up
I'd give it all up for us, it'll never be enough
I won't stop until I find my runaway love

Oh, yeah, oh, baby


Pray lyrics

Verse 1:
(And i pray)
I just can't sleep tonight,
Knowing that things ain't right.
It's in the papers, it's on the TV,
It's everywhere that i go.
Children are crying, soldiers are dying,
Some people don't have a home.

Pre Chorus:
But i know there's sunshine behind that rain,
I know there's good times behind that pain (hey)
Can you tell me how i can make a change?

Chorus:
I close my eyes, and i can see a better day,
I close my eyes and pray.
I close my eyes and i can see a better day,
I close my eyes and pray.

Verse 2:
I lose my appetite, knowing kids starve tonight
Am I a sinner? Cuz half my dinner,
Is still on my plate.
Ooh i got a vision, to make a difference,
And it's starting today.

Pre Chorus:
Cuz i know there's sunshine behind that rain,
[From: http://www.elyrics.net/read/j/justin-bieber-lyrics/pray-lyrics.html]
I know there's good times behind that pain
Heaven tell me i can make a change.

Chorus:
I close my eyes, and i can see a better day,
I close my eyes and pray. (yeee)
I close my eyes and i can see a better day,
I close my eyes and

Bridge:
I pray for the broken-hearted,
I pray for the life not started.
I pray for all the ones not breathing,
I pray for all the souls in need.
I pray, can you give em one today?

Pre Chorus:
I just can't sleep tonight,
Can someone tell me how to make a change?

End Chorus:
I close my eyes, and i can see a better day,
I close my eyes and pray, (Ooh)
I close my eyes and i can see a better day,
I close my eyes and i pray, (ooh)
I pray, I pray
I close my eyes and pray.

Somebody To Love lyrics

For you I'd write a symphony
I'd tell the violin it's time to sink or swim
Watch me play for ya

For you I'd be running a thousand miles
Just get to where you are
Step to the beat of my heart

I don't need a whole lot
But for you I need, I'd rather give you the world
Or we can share mine

I know I won't be the first one
Giving you all this attention
Baby, listen

I just need somebody to love
I, I don't need too much
Just somebody to love

Somebody to love
I don't need nothing else, I promise, girl, I swear
I just need somebody to love

I need somebody
I, I need somebody
I need somebody
I, I need somebody to love

Everyday I'd bring sun around
I'll sweep away the clouds
Smile for me

I would take every second, every single time
Spend it like my last dime
Step to the beat of my heart

I don't need a whole lot
But for you I need, I'd rather give you the world
Or we can share mine

I know I won't be the first one
Giving you all this attention
Baby, listen

I just need somebody to love
( From: http://www.elyrics.net/read/j/justin-bieber-lyrics/somebody-to-love-lyrics.html )
I, I don't need too much
Just somebody to love

Somebody to love
I don't need nothing else, I promise, girl, I swear
I just need somebody to love

I need somebody
I, I need somebody
I need somebody
I, I need somebody to love

I need somebody
I, I need somebody
I need somebody
I, I need somebody to love

And you can let it out
Anything you want
I can bring, give you the finer things, yeah

But what I really want, I can't find 'cause
Money can't find me somebody to love, oh
Find me somebody to love, oh

I need somebody to love, yeah
I, I don't need too much
Just somebody to love

Somebody to love
I don't need nothing else, I promise, girl, I swear
I just need somebody to love

I need somebody
I, I need somebody
I need somebody
I, I need somebody

I need somebody
I, I need somebody
I need somebody
I, I need somebody

I need somebody
I need somebody
I need somebody
I need somebody
I need somebody to love

Is she out there? Is she out there?
Is she out there? Is she out there?
I just need somebody to love


Smile lyrics

Ohhh yeaaah .. hhhhhhmmmmm

I wait on you forever in a day hand and foot
your world is my world, yeah
aint a way you ever gun’ get any less than you should
Cuz baby ..

(chorus)

U smile, I smile whoaaa
Cause whenever
you smile, i smile
hey hey hey

your lips my biggest weakness
shouldn't have let you know ooh
I'm always gonna do what they say
if you need me i'll come running
from a thousand miles away

(chorus)

When U smile I smile whoaaa ahh
U smile I smile hey

Baby take my open heart and all it offers
cause this is as unconditional as it’ll ever get
you ain’t seen nothing yet
[| From: http://www.elyrics.net/read/j/justin-bieber-lyrics/smile-lyrics.html |]
I wont ever hesitate to give you more
cause baby ..

U smile, I smile whoaaaa aaahh
u smile, I smile hey hey hey
U smile, I smile
I smile, I smile, I smile
U smile, I smile (make smile baby)

Baby you won't ever walk for nothin'
You are my INs and my means now
With you there's no in between
I'm all in
'Cause my card are on the table
and I'm willing and I'm able
But I'll hold to your wish 'cause is my command
hey hey hey

U smile, I smile whoaaaa
U smile, I smile hey hey hey
U smile, I smile
I smile, I smile, I smile
U smile, I smile

u smile, I smile
u smile, I smile.


U Smile lyrics

Oh, yeah, mmm

I wait on you forever, any day, hand and foot
Your world is my world, yeah
Ain't no way you ever gonna get
Any less than you should

'Cause baby, you smile, I smile, oh
'Cause whenever you smile, I smile
Hey, hey, hey

Your lips, my biggest weakness
Shouldn't have let you know
I'm always gonna do what they say, hey
If you need me, I'll come running from a thousand miles away

When you smile, I smile, oh, whoa
You smile, I smile, hey

Baby, take my open heart and all it offers
'Cause this is as unconditional as it'll ever get
You ain't seen nothing yet
[From: http://www.elyrics.net/read/j/justin-bieber-lyrics/u-smile-lyrics.html ]
I won't ever hesitate to give you more

'Cause baby, you smile, I smile, whoa
You smile, I smile, hey, hey, hey
You smile, I smile, I smile, I smile, I smile
You smile, I smile, make me smile, baby

Baby, you won't ever want for nothing
You are my ends and my means now
With you there's no in between, I'm all in

'Cause my cards are on the table
And I'm willing and I'm able
But I fold to your wish 'cause it's my command
Hey, hey, hey

You smile, I smile, whoa
You smile, I smile, hey, hey, hey
You smile, I smile, I smile, I smile, I smile
You smile, I smile, oh

You smile, I smile
You smile, I smile

Born To Be Somebody

Ohh! Ohh!

For you I'd write a symphony
I'd tell the violin
It's time to sink or swim
Watch him play for ya

For you I'd be (Whoah)
Runnin a thousand miles
Just get you where you are
Step to the beat of my heart.

I don't need a whole lot
But for you I admit I
Rather give you the world
Or we can share mine

I know that I won't be the first one
Given you all this attention
But baby listen

I just need somebody to love
I-I don't need too much

Just need somebody to love.
(Somebody to love)
I don't need nothing else
I promise , I swear.
I just need somebody to love.

I need somebody I-I need somebody
I need somebody I-I need somebody.

Everyday I bring the sun around
I sweep away the clouds.
Smile for me (Smile for me)
I would take
Every second, every single time
Spend it like my last dime.
Step to the beat of my heart.

I don't need a whole lot
But for you I admit I
Rather give you the world
Or we can share mine

I know I won't be the first one
Given you all this attention
But baby listen

I just need somebody to love (Ohh, no no no no)
[ From: http://www.elyrics.net/read/j/justin-bieber-lyrics/born-to-be-somebody-lyrics.html]
I-I don't need too much
Just need somebody to love.
(Somebody to love)

I don't need nothing else
I promise , I swear.
I just need somebody to love.

I need somebody I-I need somebody

I need somebody I-I need somebody.
(Somebody to love)
I need somebody I-I need somebody
I need somebody I-I need somebody.

And you can have it all
Anything you want I can bring
Give you the finer things, yeah
But what I really want

I can't find 'cause, money can't find me.
Somebody to love. (Ohh Whoa)

Find me somebody to love (Ohh)

I need somebody to love (Yeah)
I-I don't need too much
Just somebody to love.
Somebody to love.I don't need

nothing else,I promise I swear,I just need somebody to love.

I need somebody, I-I need somebody
I need somebody, I-I need somebody

(Somebody to love)
I need somebody, I-I need somebody
I need somebody (I swear I need somebody to love)

I-I need somebody.
Oh oh oh oh oh... etc

Is she out there
Is she out there
(repeat)

I just need somebody to love.


Can't Live Without You

I just sit here waiting for you to call
Then I wonder if you're even calling at all
So many thought go through my mind
Wish you can be here all the time
Cause I'm lost wihout you and I can't just doubt you
And there's everything about you, I just can't live
without you
Cause I'm lost wihout you and I can't just doubt you
And there's everything about you, I just can't live
without you

I'm still sitting here waiting for much more (Text me
or something)
I can't take this, I'm walking out that door
So many thought go through my mind
Wish you can be here all the time
Cause I'm lost without you and I can't just doubt you
And there's everything about you, I just live without
you

I'm breathing in, I'm breathing out
Being with you is just no doubt
I'm going crazy and there's nothing I should do
I can't, Can't live without you

I pack up my things and get on that plane
Cause without you I can't be tamed ]
So many thought go through my mind
Wish you can be here all the time
Cause I'm lost without you and I can't just doubt you
And there's everything about you, I just live without
you


I'm breathing in, I'm breathing out
Being with you is just no doubt
I'm going crazy and there's nothing I should do
I can't, Can't live without you

Please girl stay with me
My heart is waiting for you
I can't take this no more
There's nothing I should do

I'm breathing in, I'm breathing out
Being with you is just no doubt
I'm going crazy and there's nothing I should do
I can't, Can't live without

I'm breathing in, I'm breathing out
Being with you is just no doubt
I'm going crazy and there's nothing I should do
I can't, Can't live without you

Cause I'm lost without you and I can't just doubt you
And there's everything about you, I just can't live
without you


Common Denominator lyrics

It fills the air
And I fall in love with you all over again
Ooh, you're the light that faced the sun in my world
I'd face a thousand years of pain for my girl

Out of all the things in life that I could fear
Uh, the only thing that would hurt me
Is if you weren't here, woah, I don't want to go back
To just being one half of the equation
You understand what I'm sayin'?

Girl, with out you I'm lost
Can't face this focus at heart between me and love
You're the common denominator, oh, oh, ooh, oh
You're the common denominator, oh, yeah, woah

Before your love was low, now you're just my height, aye
We chase the game that would put my cot in the side
Broken heart rise up to say love is alive
You and I would stand to be multiplied, yeah

Out of all the things in life that I could fear
[ From : http://www.elyrics.net/read/j/justin-bieber-lyrics/common-denominator-lyrics.html ]
Uh, the only thing that would hurt me
Is if you weren't here, woah, I don't want to go back
To just being one half of the equation
You understand what I'm sayin'?

Girl, with out you I'm lost
Can't face this focus at heart between me and love
You're the common denominator, oh, oh, ooh, oh
You're the common denominator, oh, yeah, woah

I'm never ever not without your touch
Every kiss that you give, it gives me heart
And to all the heart it can
Jealous females hate it, I'ma hold it down for you

For you, woah, oh woah
Common denominator, oh, yeah, woah
I don't wanna to go back
Half of the equation, woah, woah, yeah
Common denominator, oh, oh, oh, oh
Common denominator, oh, yeah, woah

Just a fraction of your love fills the air
And I'd fall in love with you all over again, yeah

That Should Be Me lyrics

Everybody's laughing in my mind
Rumors spreading 'bout this other guy

Do you do what you did, what you did with me?
Does he love you the way I can?
Did you forget all the plans that you made with me?
'Cause baby, I didn't

That should be me holding your hand
That should be me making you laugh
That should be me, this is so sad
That should be me, that should be me

That should be me feeling your kiss
That should be me buying you gifts
This is so wrong, I can't go on
'Til you believe that that should be me
That should be me

You said you needed a little time for my mistakes
It's funny how you use that time to have me replaced
Did you think that I wouldn't see you out at the movies?
Whatcha doing to me?

You're taken' him where we used to go
Now if you're trying to break my heart
It's working 'cause you know

That, that should be me holding your hand
That should be me making you laugh
That should be me, this is so sad
That should be me, that should be me
[ From: http://www.elyrics.net/read/j/justin-bieber-lyrics/that-should-be-me-lyrics.html]

That should be me feeling your kiss
That should be me buying you gifts
This is so wrong, I can't go on
'Til you believe that should be me

I need to know should I fight for our love or disown?
It's getting harder to shield this pain in my heart, ooh

That should be me holding your hand
That should be me making you laugh
That should be me, this is so sad
That should be me, that should be me

That should be me feeling your kiss
That should be me buying you gifts
This is so wrong, I can't go on
'Til you believe that that should be me, ooh

Holding your hand, that should be me
The one making you laugh, oh baby
Oh, that should be me, yeah

That should be me, giving you flowers
That should be me, talking for hours
That should be me, that should be me
That should be me

Never should've let you go
I never should've let you go
That should be me
Never should've let you go
That should be me

Never should've let you go
Never should've let you go
That should be me


Baby
Featuring: Ludacris

You know you love me, I know you care
Just shout whenever, and I'll be there
You are my love, you are my heart
And we will never, ever, ever be apart

Are we an item? Girl, quit playin'
"We're just friends," what are you sayin'?
Said "there's another," and looked right in my eyes
My first love broke my heart for the first time

And I was like baby, baby, baby, oh
Like baby, baby, baby, no
Like baby, baby, baby, oh
I thought you'd always be mine, mine

Baby, baby, baby, oh
Like baby, baby, baby, no
Like baby, baby, baby, oh
I thought you'd always be mine, mine

For you, I would have done whatever
And I just can't believe we're here together
And I wanna play it cool, but I'm losin' you
I'll buy you anything, I'll buy you any ring

And I'm in pieces, baby fix me
And just shake me 'til you wake me from this bad dream
I'm goin' down, down, down, down
And I just can't believe my first love won't be around

And I'm like baby, baby, baby, oh
Like baby, baby, baby, no
( From: http://www.elyrics.net/read/j/justin-bieber-lyrics/baby-lyrics.html )
Like baby, baby, baby, oh
I thought you'd always be mine, mine

Baby, baby, baby, oh
Like baby, baby, baby, no
Like baby, baby, baby, oh
I thought you'd always be mine, mine

When I was 13, I had my first love
There was nobody that compared to my baby
And nobody came between us who could ever come above
She had me going crazy, oh I was starstruck
She woke me up daily, don't need no Starbucks

She made my heart pound
I skip a beat when I see her in the street
And at school on the playground
But I really wanna see her on a weekend
She know she got me dazin' 'cause she was so amazin'
And now my heart is breakin' but I just keep on sayin'

Baby, baby, baby, oh
Like baby, baby, baby, no
Like baby, baby, baby, oh
I thought you'd always be mine, mine

Baby, baby, baby, oh
Like baby, baby, baby, no
Like baby, baby, baby, oh
I thought you'd always be mine, mine

I'm all gone
(Yeah, yeah, yeah)
(Yeah, yeah, yeah)
Now I'm all gone
(Yeah, yeah, yeah)
(Yeah, yeah, yeah)
Now I'm all gone
(Yeah, yeah, yeah)
(Yeah, yeah, yeah)
Now I'm all gone, gone, gone, gone
I'm gone

Minggu, 16 Januari 2011

F I L A R I A S I






 

Filariasis adalah penyakit menular ( Penyakit Kaki Gajah ) yang disebabkan oleh cacing Filaria yang ditularkan oleh berbagai jenis nyamuk. Penyakit ini bersifat menahun ( kronis ) dan bila tidak mendapatkan pengobatan dapat menimbulkan cacat menetap berupa pembesaran kaki, lengan dan alat kelamin baik perempuan maupun laki-laki. Akibatnya penderita tidak dapat bekerja secara optimal bahkan hidupnya tergantung kepada orang lain sehingga memnjadi beban keluarga, masyarakat dan negara. Di Indonesia penyakit Kaki Gajah tersebar luas hampir di Seluruh propinsi. Berdasarkan laporan dari hasil survei pada tahun 2000 yang lalu tercatat sebanyak 1553 desa di 647 Puskesmas tersebar di 231 Kabupaten 26 Propinsi sebagai lokasi yang endemis, dengan jumlah kasus kronis 6233 orang. Hasil survai laboratorium, melalui pemeriksaan darah jari, rata-rata Mikrofilaria rate (Mf rate) 3,1 %, berarti sekitar 6 juta orang sudah terinfeksi cacing filaria dan sekitar 100 juta orang mempunyai resiko tinggi untuk ketularan karena nyamuk penularnya tersebar luas. Untuk memberantas penyakit ini sampai tuntas

WHO sudah menetapkan Kesepakatan Global ( The Global Goal of Elimination of Lymphatic Filariasis as a Public Health problem by The Year 2020 (. Program eliminasi dilaksanakan melalui pengobatan missal dengan DEC dan Albendazol setahun sekali selama 5 tahun dilokasi yang endemis dan perawatan kasus klinis baik yang akut maupun kronis untuk mencegah kecacatan dan mengurangi penderitanya. Indonesia akan melaksanakan eliminasi penyakit kaki gajah secara bertahap dimulai pada tahun 2002 di 5 kabupaten percontohan. Perluasan wilayah akan dilaksanakan setiap tahun. Penyebab penyakit kaki gajah adalah tiga spesies cacing filarial yaitu; Wucheria bancrofti, Brugia malayi dan Brugia timori. Vektor penular : Di Indonesia hingga saat ini telah diketahui ada 23 spesies nyamuk dari genus Anopheles, Culex, Mansonia, Aedes & Armigeres yang dapat berperan sebagai vector penular penyakit kaki gajah.

Cara Penularan :
Seseorang dapat tertular atau terinfeksi penyakit kaki gajah apabila orang tersebut digigit nyamuk yang infektif yaitu nyamuk yang mengandung larva stadium III ( L3 ). Nyamuk tersebut mendapat cacing filarial kecil ( mikrofilaria ) sewaktu menghisap darah penderita mengandung microfilaria atau binatang reservoir yang mengandung microfilaria. Siklus Penularan penyakit kaiki gajah ini melalui dua tahap, yaitu perkembangan dalam tubuh nyamuk ( vector ) dan tahap kedua perkembangan dalam tubuh manusia (hospes) dan reservoair.
Gejala klinis Filariais Akut adalah berupa ; Demam berulang-ulang selama 3 ? 5 hari, Demam dapat hilang bila istirahat dan muncul lagi setelah bekerja berat ; pembengkakan kelenjar getah bening (tanpa ada luka) didaerah lipatan paha, ketiap (lymphadenitis) yang tampak kemerahan, panas dan sakit ; radang saluran kelenjar getah bening yang terasa panas dan sakit yang menjalar dari pangkal kaki atau pangkal lengan kearah ujung (retrograde lymphangitis) ; filarial abses akibat seringnya menderita pembengkakan kelenjar getah bening, dapat pecah dan mengeluarkan nanah serta darah ; pembesaran tungkai, lengan, buah dada, buah zakar yang terlihat agak kemerahan dan terasa panas (early lymphodema). Gejal klinis yang kronis ; berupa pembesaran yang menetap (elephantiasis) pada tungkai, lengan, buah dada, buah zakar (elephantiasis skroti).

Diagnosis
Filariasis dapat ditegakkan secara Klinis ; yaitu bila seseorang tersangka Filariasis ditemukan tanda-tanda dan gejala akut ataupun kronis ; dengan pemeriksaan darah jari yang dilakukan mulai pukul 20.00 malam waktu setempat, seseorang dinyatakan sebagai penderita Filariasis, apabila dalam sediaan darah tebal ditemukan mikrofilaria. Pencegahan ; adalah dengan berusaha menghindarkan diri dari gigitan nyamuk vector ( mengurangi kontak dengan vector) misalnya dengan menggunakan kelambu bula akan sewaktu tidur, menutup ventilasi rumah dengan kasa nyamuk, menggunakan obat nyamuk semprot atau obat nyamuk baker, mengoles kulit dengan obat anti nyamuk, atau dengan cara memberantas nyamuk ; dengan membersihkan tanaman air pada rawa-rawa yang merupakan tempat perindukan nyamuk, menimbun, mengeringkan atau mengalirkan genangan air sebagai tempat perindukan nyamuk ; membersihkan semak-semak disekitar rumah.

Pengobatan :
secara massal dilakukan didaeah endemis dengan menggunakan obat Diethyl Carbamazine Citrate (DEC) dikombinasikan dengan Albenzol sekali setahun selama 5 ? 10 tahun, untuk mencegah reaksi samping seperti demam, diberikan Parasetamol ; dosis obat untuk sekali minum adalah, DEC 6 mg/kg/berat badan, Albenzol 400 mg albenzol (1 tablet ) ; pengobatan missal dihentikan apabila Mf rate sudah mencapai < 1 % ; secara individual / selektif; dilakukan pada kasus klinis, baik stadium dini maupun stadium lanjut, jenis dan obat tergantung dari keadaan kasus.